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LSU Life Course and Aging Center seeks secrets to "aging successfully"

Somewhere in Louisiana, there is a man in his 80s jogging or planning an afternoon tennis match. Somewhere else in the state, there is a man in his 80s who is bedridden, tended to by a nurse or family members.

How is one elderly man able to live an active lifestyle, while another his age is overwhelmed by the effects of time? Researchers in LSU's new Life Course and Aging Center are seeking the answer to this and many other questions.

According to some government projections, the number of U.S. residents over the age of 65 will rise to 70.3 million by the year 2030, more than twice their number in 2000. Similar growth is predicted for Louisiana, with the state's 65-and-over population almost doubling by 2025.

With these growing numbers comes a need to better understand the aging process in all its aspects -- physical, mental and emotional -- in order to ensure the "successful aging" of the population. That's why the diverse LSU faculty that make up the Life Course and Aging Center are conducting major research projects on the aging process, from birth through the later years of life.

The Life Course and Aging Center is a multidisciplinary effort of faculty from a number of LSU departments and campuses. It was officially approved by the Board of Regents over the summer, but the effort to form the center and the research being conducted by its members have been going on for some time.

Katie Cherry, chair of LSU's Department of Psychology and a leader in the drive to form the Center, is a specialist in cognitive aging, particularly memory and related processes in older adults. She is also one of the primary investigators in a major five-year study called the "Multidisciplinary Study of Longevity and Healthy Aging in the Louisiana Population" or, simply, the "Louisiana Healthy Aging Study." The study is supported by a $4.1 million Health Excellence Fund grant from the Board of Regents and is headed up by Dr. S. Michal Jazwinski of the LSU Health Sciences Center in New Orleans.

The study began with Jazwinski, who has been involved in aging research for almost two decades. Jazwinski was concentrating on the role of genes in longevity and working with subjects in New Orleans when he realized that the issue needed to be examined from a variety of angles -- molecular, physiological, psychological and so on. That's when Cherry, LSU Kinesiology Associate Professor Robert Wood, LSU Biological Sciences Professor Mark Batzer and others involved in the center entered the picture.

The study involves testing some 780 subjects over a five-year period, with 260 over the age of 90. It is a population-based study, meaning that the subjects represent a random sampling of the entire population in a 12-parish area within a 40-mile radius of Baton Rouge.

The subjects receive a battery of tests conducted at the Pennington Biomedical Research Center in Baton Rouge, including blood work, physical function tests, and cognitive measurements. After this stage, there are follow-up visits at home for those over 90.

"We're trying to find what characteristics have allowed these people to live so long," said Cherry. "We hope to find some aspects of their metabolisms or lives that have predisposed them to live so long."

To this end, each researcher concentrates on their specific area. For instance, Cherry conducts the tests to measure cognitive ability, while Wood works to assess the functional abilities in a quantitative way. In order for Wood to assess the elderly participants, he has them conduct tasks they would encounter during daily living -- emptying a load of laundry, carrying grocery bags a certain distance.

"We're already seeing interesting trends, however, before we make any definitive statements, we need to test additional subjects," said Jazwinski. "We are establishing grounds for the next stages (of the study) and testing new hypotheses. It's an ongoing process that, if successful, will continue for quite some time." Despite the massive scope and importance of the Louisiana Healthy Aging Study, Cherry and the others are quick to point out that the center is involved in a great deal of additional research.

"We have expertise at the other end of the lifespan as well -- early childhood development," Cherry explained. "The Life Course and Aging Center is sincerely what it says: development through all stages, infant to early childhood to teens and adults."

For instance, she said, Jill Suitor, a professor in LSU's Department of Sociology, has a grant of more than $1 million from the National Institute on Aging to study parent-adult child relationships. This project, which is housed at LSU, is in collaboration with Karl Pillemer, a professor in the Department of Human Development at Cornell University.

In addition, Pam Monroe, Carville Professor of Human Ecology and Associate Dean of the Graduate School at LSU, is studying young and middle-aged women living in poverty and their children. She is concentrating on women and children in rural areas and, with the aid of several grants, examining how social policies -- particularly welfare reform -- are affecting them across the life span. Monroe has been collecting data on women around the state since 1996 and worked with the state Department of Social Services on a welfare evaluation project.

"We are all very committed to the life course perspective," said Monroe. "It reminds us that an older person doesn't get to be who they are overnight. They have been 'becoming' that since childhood and it's a culmination of socioeconomic status, genetics, health, well-being and environment across the life span."

For more information on the Life Course and Aging Center at LSU, visit the Web site at http://www.lsuagingstudies.com or contact Katie Cherry at 225-578-4099 or pskatie@lsu.edu.


Other Useful Websites

United States Senate Special Committee on Aging


Newsletter

The Life Course and Aging Center publishes a newsletter describing center activities during the past year. The 2006, 2005, 2004, 2003, and 2001 newsletters are available for download (PDF format).